{"id":8711,"date":"2022-10-19T10:10:13","date_gmt":"2022-10-19T02:10:13","guid":{"rendered":"https:\/\/newsletter.tcu.edu.tw\/?p=8711"},"modified":"2023-09-25T16:29:46","modified_gmt":"2023-09-25T08:29:46","slug":"%e6%85%88%e5%a4%a7%e9%86%ab%e5%ad%b8%e9%99%a2%e3%80%8a%e5%a4%a7%e5%b8%ab%e5%82%b3%e7%bf%92%e7%b3%bb%e5%88%97%e3%80%8b%e4%b8%ad%e7%a0%94%e9%99%a2%e5%8a%89%e6%89%b6%e6%9d%b1%e5%89%af%e9%99%a2%e9%95%b7","status":"publish","type":"post","link":"https:\/\/newsletter.tcu.edu.tw\/?p=8711","title":{"rendered":"\u6148\u5927\u91ab\u5b78\u9662\u300a\u5927\u5e2b\u50b3\u7fd2\u7cfb\u5217\u300b\u4e2d\u7814\u9662\u5289\u6276\u6771\u526f\u9662\u9577\u5206\u4eab\u534a\u4e73\u7cd6\u51dd\u96c6\u7d20\u5967\u79d8"},"content":{"rendered":"<p class=\"p1\" style=\"text-align: justify;\"><span class=\"s1\">\u6587<\/span><span class=\"s2\">\/<\/span><span class=\"s1\">\u7167\u7247\uff1a\u6797\u7693\u7136\u3001\u91ab\u5b78\u9662<\/span><\/p>\n<p class=\"p2\" style=\"text-align: justify;\"><span class=\"s1\">\u6148\u6fdf\u5927\u5b78\u91ab\u5b78\u9662\u300a\u5927\u5e2b\u50b3\u7fd2\u7cfb\u5217\u300b\uff0c\u56e0\u61c9\u570b\u5167\u75ab\u60c5\u8b8a\u5316\u63a1\u300c\u5be6\u9ad4\u53ca\u7dda\u4e0a\u300d\u96d9\u8ecc\u65b9\u5f0f\u8fa6\u7406\uff0c\u8b93\u7121\u6cd5\u89aa\u81e8\u6703\u5834\u6148\u5927\u5e2b\u751f\u53ca\u6148\u6fdf\u5fd7\u696d\u9ad4\u540c\u4ec1\u80fd\u5920\u7570\u5730\u591a\u65b9\u9023\u7dda\uff0c\u8b93\u5c08\u696d\u5b78\u7fd2\u4e0d\u6253\u6298\uff0c\u540c\u6642\u4e5f\u5b88\u8b77\u5e2b\u751f\u8207\u540c\u4ec1\u5011\u7684\u5065\u5eb7\u3002<\/span><\/p>\n<p class=\"p2\" style=\"text-align: justify;\"><span class=\"s1\">\u4e2d\u592e\u7814\u7a76\u9662\u5289\u6276\u6771\u526f\u9662\u9577\u540c\u6642\u4e5f\u662f\u6148\u6fdf\u5927\u5b78\u8b1b\u5ea7\u6559\u6388\uff0c\u9032\u884c<\/span><span class=\"s2\">Galectins and intracellular innate immunity: recognition of cytosolic glycans (<\/span><span class=\"s1\">\u534a\u4e73\u7cd6\u51dd\u96c6\u7d20\u548c\u7d30\u80de\u5167\u5148\u5929\u514d\u75ab\uff1a\u7d30\u80de\u8cea\u805a\u91a3\u7684\u8b58\u5225<\/span><span class=\"s2\">)<\/span><span class=\"s1\">\u7684\u5b78\u8853\u6f14\u8b1b\uff0c\u8b93\u807d\u773e\u77ad\u89e3<\/span><span class=\"s2\">galectin<\/span><span class=\"s1\">\u5982\u4f55\u8abf\u7bc0\u7d30\u80de\u5167\u7684\u514d\u75ab\u6a5f\u5236\u4f8b\u5982\u767c\u708e\u8207\u81ea\u566c<\/span><span class=\"s2\">(autophagy)<\/span><span class=\"s1\">\uff0c\u5f9e\u800c\u4fdd\u8b77\u5bbf\u4e3b\u514d\u53d7\u7d30\u83cc\u611f\u67d3\uff1b\u900f\u904e\u6b64\u6a5f\u8f49\u5728\u672a\u4f86\u6216\u8a31\u53ef\u63d0\u4f9b\u6557\u8840\u75c7\u7684\u6cbb\u7642\u65b9\u91dd\uff0c\u4ee5\u63d0\u9ad8\u611f\u67d3\u8005\u7684\u5b58\u6d3b\u7387\u3001\u5ef6\u9577\u6551\u6cbb\u7684\u9ec3\u91d1\u6642\u9593\u3002<\/span><\/p>\n<p class=\"p2\" style=\"text-align: justify;\"><span class=\"s1\">\u5289\u6276\u6771\u526f\u9662\u9577\u7814\u7a76\u8457\u91cd\u65bc\u63a2\u7a76\u534a\u4e73\u7cd6\u51dd\u96c6\u7d20\u5728\u708e\u75c7\u3001\u5148\u5929\u514d\u75ab\u3001\u764c\u75c7\u8207\u80a5\u80d6\u65b9\u9762\u7684\u529f\u80fd\uff0c\u4e26\u4ee5\u6b64\u70ba\u57fa\u790e\uff0c\u81f4\u529b\u767c\u5c55\u534a\u4e73\u7cd6\u51dd\u96c6\u7d20\u7684\u6291\u88fd\u5291\uff0c\u7528\u65bc\u708e\u6027\u75be\u75c5\u548c\u764c\u75c7\u7684\u6cbb\u7642\u3002\u4e26\u66fe\u70ba\u570b\u5bb6\u578b\u91a3\u79d1\u5b78\u4e2d\u7db1\u8a08\u756b\u7e3d\u4e3b\u6301\u4eba\uff0c\u81f4\u529b\u63a8\u5ee3\u91a3\u79d1\u5b78\u5728\u81fa\u7063\u7684\u7814\u7a76\u3002\u4e26\u65bc<\/span><span class=\"s2\">2019<\/span><span class=\"s1\">\u5e74<\/span><span class=\"s2\">12<\/span><span class=\"s1\">\u6708\u7372\u9078\u70ba\u300c\u7f8e\u570b\u570b\u5bb6\u767c\u660e\u5bb6\u5b78\u9662\uff08<\/span><span class=\"s2\">National Academy of Inventors, NAI<\/span><span class=\"s1\">\uff09\u300d\u9662\u58eb\uff0c\u70ba\u5b78\u8853\u767c\u660e\u5bb6\u7684\u6700\u9ad8\u5c08\u696d\u69ae\u8b7d\u4e4b\u4e00\u3002<\/span><\/p>\n<p class=\"p2\" style=\"text-align: justify;\"><span class=\"s1\">\u6f14\u8b1b\u6d3b\u52d5\u7531\u91ab\u5b78\u9662\u8b1d\u5764\u53e1\u526f\u9662\u9577\u4e3b\u6301\uff0c\u6d3b\u52d5\u70ba\u5168\u82f1\u6587\u6f14\u8b1b\uff1b\u9664\u6f14\u8b1b\u5916\uff0c\u4e5f\u5b89\u6392\u535a\u58eb\u73ed\u5b78\u751f\u9032\u884c\u8ad6\u6587\u4e3b\u984c\u5831\u544a\uff0c\u540c\u6642\u570b\u969b\u5b78\u751f\u4e5f\u8e34\u8e8d\u51fa\u5e2d\u3002\u6f14\u8b1b\u5f8c\uff0c\u91ab\u79d1\u6240\u535a\u58eb\u73ed\u56db\u5e74\u7d1a\u5b78\u751f\u9ec3\u5a01\u7ff0\u91ab\u5e2b\u63d0\u554f\u300c\u5728\u81e8\u5e8a\u8ddf\u784f\u7a76\u4e0a\uff0c\u76ee\u524d\u4e5f\u77e5\u9053<\/span><span class=\"s2\">galectin-3<\/span><span class=\"s1\">\u8207\u764c\u75c7\u6709\u606f\u606f\u76f8\u95dc\uff0c\u76ee\u524d\u4e5f\u5df2\u7d93\u6709\u958b\u59cb\u7814\u767c\u91dd\u5c0d<\/span><span class=\"s2\">galectin-3<\/span><span class=\"s1\">\u7684\u764c\u75c7\u6cbb\u7642\uff0c\u8acb\u554f\u9662\u58eb\u5c0d\u6b64\u6709\u4ec0\u9ebc\u770b\u6cd5\u55ce\uff1f\u300d\uff0c\u5289\u526f\u9662\u9577\u7b54\u5fa9\u300c\u76ee\u524d\u6211\u5011\u5df2\u77e5\u5169\u8005\u662f\u6709\u5f88\u5bc6\u5207\u7684\u95dc\u4fc2\u3002\u4f46\u50cf\u5728\u65e9\u671f\u7684\u6642\u5019\uff0c\u96d6\u7136\u6211\u5011\u77e5\u9053\u5169\u8005\u6709\u95dc\uff0c\u4f46\u9084\u4e0d\u592a\u4e86\u89e3\u5169\u8005\u4e4b\u9593\u7684\u6a5f\u5236\uff0c\u6240\u4ee5\u6709\u4e00\u4e9b\u516c\u53f8\u7684\u7814\u767c\u65b9\u5411\u5728\u65e9\u671f\u7684\u6642\u5019\u5c31\u5df2\u7d93\u932f\u4e86\uff0c\u4e5f\u5c0e\u81f4\u85e5\u7269\u4e0d\u4e00\u5b9a\u6709\u6548\u3002\u7576\u7136\u91dd\u5c0d<\/span><span class=\"s2\">galectin<\/span><span class=\"s1\">\u7684\u6cbb\u7642\u65b9\u5f0f\u662f\u6709\u4e00\u5b9a\u7684\u6f5b\u529b\uff0c\u4f46\u5b83\u662f\u5426\u70ba\u6700\u597d\u7684\u6cbb\u7642\u6a19\u7684\u6211\u5011\u4f9d\u7136\u4e0d\u77e5\u9053\uff1b\u90a3\u5373\u4fbf\u6211\u5011\u77e5\u9053\u5b83\u662f\u4e00\u500b\u6cbb\u7642\u7684\u76ee\u6a19\uff0c\u6211\u5011\u8981\u627e\u51fa\u91dd\u5c0d\u5b83\u7684\u6291\u5236\u5291\u4e5f\u4e0d\u662f\u4e00\u4ef6\u5bb9\u6613\u7684\u4e8b\u300d\u3002<\/span><\/p>\n<p class=\"p2\" style=\"text-align: justify;\"><span class=\"s1\">\u6148\u6fdf\u5927\u5b78\u91ab\u79d1\u6240\u535a\u58eb\u73ed\u4e09\u5e74\u7d1a\u5948\u53ca\u5229\u4e9e\u570b\u969b\u751f<\/span><span class=\"s2\">Ibiayo Ayooluwa Gabriel<\/span><span class=\"s1\">\u63d0\u554f\u300c<\/span><span class=\"s2\">Glycan<\/span><span class=\"s1\">\u7684\u553e\u6db2\u9178\u5316<\/span><span class=\"s2\">(sialyation)<\/span><span class=\"s1\">\u6703\u5f71\u97ff\u4e00\u500b\u75be\u75c5\u7684\u767c\u751f\uff0c\u8acb\u554f\u5b83\u662f\u900f\u904e\u4ec0\u9ebc\u6a23\u7684\u6a5f\u5236\u53bb\u5f71\u97ff\u5462\uff1f\u300d\uff0c\u5289\u526f\u9662\u9577\u8868\u793a\u300c\u5b83\u53ef\u80fd\u662f\u900f\u904e\u5728\u7d30\u80de\u819c\u8868\u9762\u5c0d\u7cd6\u86cb\u767d\u9032\u884c\u553e\u6db2\u9178\u5316\u5f9e\u800c\u5f71\u97ff\u4e0b\u6e38\u7684\u8def\u5f91\uff0c\u4f8b\u5982\u8abf\u7bc0\u767c\u708e\u8207\u81ea\u566c\u3002\u300d<\/span><\/p>\n<p class=\"p3\" style=\"text-align: justify;\"><span class=\"s1\">\u904e\u53bb\u5e7e\u5e74\uff0c\u5289\u526f\u9662\u9577\u6bcf\u5e74\u90fd\u5230\u6148\u6fdf\u5927\u5b78\u6f14\u8b1b\uff0c\u5206\u4eab\u7814\u7a76\u7d93\u9a57\uff0c\u4e26\u5354\u52a9\u6307\u5c0e\u91ab\u5b78\u9662\u5e2b\u751f\u8207\u7cfb\u6240\u7684\u7814\u7a76\u767c\u5c55\uff0c\u5e0c\u671b\u4fc3\u9032\u6148\u6fdf\u5927\u5b78\u8207\u91ab\u7642\u5fd7\u696d\u7684\u751f\u91ab\u7814\u7a76\u8207\u8f49\u8b6f\u91ab\u5b78\u4e4b\u63d0\u5347\u8207\u767c\u5c55\uff0c\u4e26\u5354\u52a9\u63d0\u5347\u6148\u6fdf\u5927\u5b78\u7814\u7a76\u4e4b\u570b\u969b\u5316\u3002\u6f14\u8b1b\u5c3e\u8072\uff0c\u6148\u6fdf\u5927\u5b78\u5289\u6021\u5747\u6821\u9577\u53ca\u91ab\u5b78\u9662\u8b1d\u5764\u53e1\u526f\u9662\u9577\u4ee3\u8868\u5168\u9ad4\u6148\u5927\u5e2b\u751f\u5411\u5289\u6276\u6771\u526f\u9662\u9577\u8868\u9054\u8b1d\u610f\uff0c\u8b93\u5728\u5ea7\u53ca\u5728\u7dda\u4e0a\u7684\u6559\u8077\u54e1\u751f\u7686\u7372\u76ca\u826f\u591a\u3001\u6536\u7a6b\u6eff\u6eff\u3002<\/span><\/p>\n<p><a href=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/1-5.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-8712 size-full\" src=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/1-5.jpg\" alt=\"\" width=\"1024\" height=\"683\" srcset=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/1-5.jpg 1024w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/1-5-300x200.jpg 300w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/1-5-768x512.jpg 768w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/1-5-730x487.jpg 730w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/1-5-435x290.jpg 435w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/1-5-272x182.jpg 272w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a> <a href=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/2-6.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-8713 size-full\" src=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/2-6.jpg\" alt=\"\" width=\"1024\" height=\"683\" srcset=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/2-6.jpg 1024w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/2-6-300x200.jpg 300w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/2-6-768x512.jpg 768w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/2-6-730x487.jpg 730w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/2-6-435x290.jpg 435w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/2-6-272x182.jpg 272w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a> <a href=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/3-5.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-8714 size-full\" src=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/3-5.jpg\" alt=\"\" width=\"1024\" height=\"683\" srcset=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/3-5.jpg 1024w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/3-5-300x200.jpg 300w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/3-5-768x512.jpg 768w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/3-5-730x487.jpg 730w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/3-5-435x290.jpg 435w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2022\/10\/3-5-272x182.jpg 272w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6587\/\u7167\u7247\uff1a\u6797\u7693\u7136\u3001\u91ab\u5b78\u9662 \u6148\u6fdf\u5927\u5b78\u91ab\u5b78\u9662\u300a\u5927\u5e2b\u50b3\u7fd2\u7cfb\u5217\u300b\uff0c\u56e0 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":8714,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-8711","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-5","clearfix"],"_links":{"self":[{"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/8711","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8711"}],"version-history":[{"count":1,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/8711\/revisions"}],"predecessor-version":[{"id":12877,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/8711\/revisions\/12877"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/media\/8714"}],"wp:attachment":[{"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8711"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8711"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8711"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}