{"id":2537,"date":"2018-03-27T17:09:13","date_gmt":"2018-03-27T09:09:13","guid":{"rendered":"https:\/\/newsletter.tcu.edu.tw\/?p=2537"},"modified":"2023-09-22T10:39:17","modified_gmt":"2023-09-22T02:39:17","slug":"%e8%a6%96%e7%a5%9e%e7%b6%93%e5%b0%8f%e4%b8%ad%e9%a2%a8%e7%9a%84%e6%b2%bb%e7%99%82%e6%96%b0%e7%99%bc%e7%8f%be-p-%e9%81%b8%e6%93%87%e7%b4%a0%e5%b5%8c%e5%90%88%e8%9b%8b%e7%99%bd","status":"publish","type":"post","link":"https:\/\/newsletter.tcu.edu.tw\/?p=2537","title":{"rendered":"\u8996\u795e\u7d93\u5c0f\u4e2d\u98a8\u7684\u6cbb\u7642\u65b0\u767c\u73fe-\u201cP-\u9078\u64c7\u7d20\u5d4c\u5408\u86cb\u767d\u201d"},"content":{"rendered":"

\u6587\uff0f\u7167\u7247:\u9ec3\u821c\u5e73<\/p>\n

\u8996\u795e\u7d93\u5c0f\u4e2d\u98a8\u70ba50\u6b72\u4ee5\u4e0a\u65cf\u7fa4\u6700\u5e38\u898b\u7684\u6025\u6027\u8996\u795e\u7d93\u7f3a\u8840\u6027\u75c5\u8b8a\uff0c\u5927\u591a\u6578\u60a3\u8005\u6703\u7a81\u7136\u7684\u8996\u529b\u4e0b\u964d\uff0c\u6216\u4e0a\u4e0b\u65b9\u7684\u8996\u91ce\u7522\u751f\u5c0f\u90e8\u5206\u7f3a\u640d\u3002\u4e3b\u8981\u6210\u56e0\u70ba\u8996\u795e\u7d93\u76e4\u7684\u8840\u6db2\u4f9b\u61c9\u4e0d\u8db3\uff0c\u5f15\u767c\u8996\u795e\u7d93\u7d44\u7e54\u7f3a\u6c27\uff0c\u9020\u6210\u8996\u795e\u7d93\u6c34\u816b\uff0c\u751a\u6216\u51fa\u8840\uff0c\u6700\u7d42\u5c0e\u81f4\u8996\u795e\u7d93\u640d\u50b7\uff0c\u91ab\u5b78\u4e0a\u7a31\u4e4b\u70ba\u300c\u524d\u90e8\u8996\u795e\u7d93\u7f3a\u8840\u6027\u75c5\u8b8a\u300d\u3002\u6148\u6fdf\u5927\u5b78\u5206\u5b50\u751f\u7269\u66a8\u4eba\u985e\u907a\u50b3\u5b78\u7cfb\u9ec3\u821c\u5e73\u526f\u6559\u6388\u5718\u968a\u8207\u91ab\u79d1\u6240\u8521\u69ae\u5764\u6240\u9577\u5718\u968a\u5408\u4f5c\uff0c\u70ba\u9019\u9577\u671f\u4ee5\u4f86\u7f3a\u4e4f\u6709\u6548\u6cbb\u7642\u65b9\u5f0f\u7684\u75be\u75c5\u627e\u51fa\u89e3\u65b9\uff0c\u6b64\u9805\u7814\u7a76\u4e3b\u8981\u7531\u5206\u5b50\u751f\u7269\u66a8\u4eba\u985e\u907a\u50b3\u5b78\u7cfb\u78a9\u58eb\u73ed\u7814\u7a76\u751f Kishan Kapupara\u5b8c\u6210\u91cd\u8981\u6027\u5de5\u4f5c\uff0c\u4e26\u65bc2017\u5e7411\u6708\u767c\u8868\u5728\u570b\u969b\u8f49\u8b6f\u91ab\u5b78\u91cd\u8981\u671f\u520a Cell Death & Disease\u4e0a\u3002<\/p>\n

\u7814\u7a76\u5718\u968a\u5229\u7528\u7a7f\u900f\u5f0f\u96fb\u5b50\u986f\u5fae\u93e1(Transmission electron microscope) \u767c\u73fe\u7576\u7d66\u4e88\u6709\u524d\u90e8\u8996\u795e\u7d93\u7f3a\u8840\u6027\u75c5\u8b8a\u7684\u5927\u9f20P-\u9078\u64c7\u7d20\u5d4c\u5408\u86cb\u767d(P-selectin IgG Chimera)\u6cbb\u7642\u6642\uff0c\u53ef\u7dad\u6301\u8996\u795e\u7d93\u8840\u7ba1\u969c\u58c1\u7684\u5b8c\u6574\u6027\uff0c\u4e26\u900f\u904e\u6d3b\u5316NF-E2\u76f8\u95dc\u56e0\u5b502\uff08nuclear factor erythroid-2-related factor, Nrf2)\u7684\u8a0a\u606f\u8def\u5f91\uff0c\u6709\u6548\u7684\u5728\u6025\u6027\u671f\u6e1b\u5c11\u767c\u708e\u53cd\u61c9\uff0c\u9032\u800c\u4fdd\u8b77\u8996\u795e\u7d93\u7bc0\u7d30\u80de\uff0c\u6e1b\u5c11\u8996\u795e\u7d93\u7bc0\u7d30\u80de\u7684\u51cb\u4ea1\u53ca\u7dad\u6301\u8996\u89ba\u529f\u80fd\u3002<\/p>\n

\u9ec3\u821c\u5e73\u535a\u58eb\u7814\u7a76\u5718\u968a\u5c07\u4ee5\u6b64\u75be\u75c5\u52d5\u7269\u6a21\u5f0f\uff0c\u9032\u4e00\u6b65\u6e2c\u8a66\u76ee\u524d\u4eba\u9ad4\u8a66\u9a57\u4e2d\u5df2\u7d93\u4f7f\u7528\u7684Nrf2\u6d3b\u5316\u5291\uff0c\u6df1\u5165\u7684\u95e1\u660e\u5176\u4f5c\u7528\u65bc\u795e\u7d93\u7d30\u80de\u8207\u8abf\u63a7\u6297\u767c\u708e\u8207\u6297\u7d30\u80de\u51cb\u4ea1\u7684\u6a5f\u5236\uff0c\u5728\u672a\u4f86\u5c07\u53ef\u5728\u81e8\u5e8a\u4e0a\u61c9\u7528\u65bc\u524d\u90e8\u8996\u795e\u7d93\u7f3a\u8840\u6027\u75c5\u8b8a\u7684\u9810\u9632\u8207\u6cbb\u7642\u3002<\/p>\n

\u8ad6\u6587\u9023\u7d50: https:\/\/www.nature.com\/articles\/cddis2017566.pdf<\/a><\/p>\n

\"\"<\/a> \"\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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