{"id":2432,"date":"2018-03-01T11:05:05","date_gmt":"2018-03-01T03:05:05","guid":{"rendered":"https:\/\/newsletter.tcu.edu.tw\/?p=2432"},"modified":"2023-09-22T10:32:43","modified_gmt":"2023-09-22T02:32:43","slug":"%e6%85%88%e5%a4%a7%e5%8a%89%e6%80%a1%e5%9d%87%e7%a0%94%e7%a9%b6%e5%9c%98%e9%9a%8a%e7%99%bc%e7%8f%be%e8%aa%bf%e6%8e%a7%e5%89%b5%e5%82%b7%e8%a8%98%e6%86%b6%e7%9a%84%e5%9f%ba%e5%9b%a0-%e5%8f%af%e6%9c%9b","status":"publish","type":"post","link":"https:\/\/newsletter.tcu.edu.tw\/?p=2432","title":{"rendered":"\u6148\u5927\u5289\u6021\u5747\u7814\u7a76\u5718\u968a\u767c\u73fe\u8abf\u63a7\u5275\u50b7\u8a18\u61b6\u7684\u57fa\u56e0  \u53ef\u671b\u61c9\u7528\u65bc\u5275\u50b7\u5f8c\u58d3\u529b\u75c7\u5019\u7fa4\u6cbb\u7642"},"content":{"rendered":"<p>\u6587:\u674e\u5bb6\u8413<\/p>\n<p>\u300c\u8001\u9f20\u770b\u5230\u8c93\u6703\u9003\uff0c\u807d\u5230\u5de8\u5927\u8072\u97ff\u6211\u5011\u6703\u7279\u5225\u8b66\u6212\uff0c\u9069\u5ea6\u7684\u5bb3\u6015\u5728\u52d5\u7269\u6f14\u5316\u4e0a\u662f\u597d\u7684\uff0c\u53ef\u4ee5\u5e6b\u52a9\u751f\u5b58\uff0c\u4f46\u82e5\u662f\u904e\u5ea6\u6050\u61fc\uff0c\u5c31\u6703\u5f71\u97ff\u5230\u6b63\u5e38\u7684\u751f\u6d3b\u3002\u300d\u56e0\u70ba\u6050\u61fc\u7684\u8868\u73fe\u5f71\u97ff\u5f88\u5927\uff0c\u6148\u6fdf\u5927\u5b78\u91ab\u5b78\u79d1\u5b78\u7814\u7a76\u6240\u5289\u6021\u5747\u6559\u6388\u5e36\u9818\u7684\u7814\u7a76\u5718\u968a\u7d93\u904e\u4e03\u5e74\u7684\u9577\u6642\u9593\u7814\u7a76\uff0c\u5728\u4eca\u5e74\u4e8c\u6708\u7684\u570b\u969b\u671f\u520a-\u5206\u5b50\u795e\u7d93\u79d1\u5b78\u524d\u6cbf (Frontiers in Molecular Neuroscience)\u767c\u8868\u4e86\u4e00\u7bc7\u95dc\u65bc\u5275\u50b7\u8a18\u61b6\u8abf\u63a7\u7684\u7814\u7a76\u8ad6\u6587\uff0c\u767c\u73feATF3\u57fa\u56e0\u5f71\u97ff\u5230\u5275\u50b7\u8a18\u61b6\u7684\u8868\u9054\u3002<\/p>\n<p>\u5728\u707d\u96e3\u6216\u5275\u50b7\u7d93\u9a57\u767c\u751f\u5f8c\uff0c\u6709\u4e9b\u4eba\u5f88\u5feb\u5c31\u80fd\u6062\u5fa9\uff0c\u56de\u5230\u751f\u6d3b\u5e38\u8ecc\uff0c\u7e7c\u7e8c\u5f80\u524d\u8d70\uff0c\u4f46\u6709\u4e9b\u4eba\u537b\u7559\u5728\u5275\u50b7\u88e1\u8d70\u4e0d\u51fa\u4f86\uff0c\u6703\u6709\u5f88\u5e38\u4e00\u6bb5\u6642\u9593\u986f\u793a\u9000\u7e2e\u3001\u5931\u53bb\u52d5\u6a5f\u3001\u6050\u61fc\u3001\u5931\u7720\u7b49\u5275\u50b7\u5f8c\u58d3\u529b\u75c7\u5019\u7fa4(Post Traumatic Stress Disorders,\u7c21\u7a31PTSD)\u7684\u75c7\u72c0\uff0c\u75c7\u72c0\u56b4\u91cd\u8005\uff0c\u751a\u81f3\u5f71\u97ff\u5176\u751f\u6d3b\u53ca\u5de5\u4f5c\uff0c\u8a31\u591a\u60a3\u8005\u82e5\u4e0d\u7d93\u904e\u6cbb\u7642\uff0c\u53ef\u80fd\u9918\u751f\u90fd\u8d70\u4e0d\u51fa\u9019\u5275\u50b7\u7d93\u9a57\u3002<\/p>\n<p>\u5289\u6021\u5747\u6559\u6388\u5728\u5730\u9707\u5f8c\uff0c\u5230\u4e2d\u83ef\u570b\u5c0f\u95dc\u61f7\u707d\u6c11\uff0c\u5289\u6559\u6388\u8868\u793a\uff0c\u7576\u6642\u4ed6\u770b\u5230\u6709\u4e9b\u4eba\u628a\u81ea\u5df1\u7528\u68c9\u88ab\u5305\u8d77\u4f86\uff0c\u767d\u5929\u4e5f\u5728\u7761\u89ba\uff0c\u6216\u662f\u7e2e\u5728\u89d2\u843d\uff0c\u9019\u90fd\u662f\u906d\u9047\u5230\u5275\u50b7\u5f8c\u7684\u75c7\u72c0\u3002\u5289\u6021\u5747\u6559\u6388\u9032\u4e00\u6b65\u8868\u793a\uff0c\u89aa\u4eba\u7684\u966a\u4f34\uff0c\u5718\u9ad4\u7684\u652f\u6301\u53ef\u4ee5\u6e1b\u8f15\u5275\u50b7\u5f8c\u58d3\u529b\u75c7\u5019\u7fa4\u7684\u75c7\u72c0\uff0c\u6216\u8005\u52a0\u901f\u6062\u5fa9\uff0c\u4f46\u6709\u5c11\u6578\u60a3\u8005\u7531\u65bc\u5148\u5929\u57fa\u56e0\u7684\u5f71\u97ff\uff0c\u6050\u61fc\u8a18\u61b6\u4e00\u65e6\u5f62\u6210\uff0c\u4e0d\u6613\u6e1b\u7de9\uff0c\u6545\u767c\u5c55\u6210\u9577\u671f\u7684\u6182\u9b31\u75c7\u6216\u8005\u8868\u73fe\u7126\u616e\u75be\u60a3(anxiety disorders)\u5fb5\u72c0\u3002\u5728\u82b1\u84ee\u7d93\u904e\u5927\u5730\u9707\u5f8c\uff0c\u80fd\u5920\u4e86\u89e3\u8a72\u57fa\u56e0\u5c0d\u60c5\u7dd2\u7684\u5f71\u97ff\uff0c\u751a\u81f3\u672a\u4f86\u53ef\u4ee5\u627e\u5230\u8abf\u63a7\u8a72\u57fa\u56e0\u8868\u73fe\u7684\u85e5\u7269\uff0c\u6df1\u5177\u610f\u7fa9<\/p>\n<p>\u5289\u6021\u5747\u6559\u6388\u8868\u793a\uff0c\u6050\u61fc\u5728\u751f\u7269\u6f14\u5316\u7684\u6b77\u7a0b\u4e2d\uff0c\u6709\u52a9\u65bc\u8da8\u5409\u907f\u51f6\u3002\u9069\u5ea6\u7684\u6050\u61fc\u8a18\u61b6\uff0c\u53ef\u907f\u514d\u5929\u6575\u4ee5\u53ca\u5371\u96aa\uff0c\u589e\u52a0\u751f\u5b58\u6a5f\u7387\uff0c\u5982\u679c\u6050\u61fc\u8a18\u61b6\u592a\u6df1\u523b\uff0c\u7121\u6cd5\u9069\u61c9\u65b0\u7684\u60c5\u6cc1\uff0c\u5c31\u6703\u5c0e\u81f4\u5927\u8166\u5167\u6050\u61fc\u8a18\u61b6\u904e\u5ea6\u7d2f\u7a4d\uff0c\u6210\u4e86\u9a5a\u5f13\u4e4b\u9ce5\uff0c\u5f88\u5bb9\u6613\u56e0\u70ba\u5c0f\u5c0f\u7684\u7a81\u767c\u60c5\u6cc1\u5c31\u7dca\u5f35\uff0c\u5fc3\u8df3\u52a0\u901f\uff0c\u8840\u58d3\u589e\u52a0\uff0c\u58d3\u529b\u8377\u723e\u8499\u6025\u901f\u5206\u6ccc\uff0c\u56b4\u91cd\u8005\u5931\u53bb\u60c5\u7dd2\u63a7\u5236\uff0c\u5f71\u97ff\u65e5\u5e38\u5de5\u4f5c\u8207\u751f\u6d3b\u3002<\/p>\n<p>\u70ba\u4e86\u4e86\u89e3\u70ba\u4f55\u5275\u50b7\u5f8c\u58d3\u529b\u75c7\u5019\u7fa4\u7684\u60a3\u8005\u8f03\u4e00\u822c\u4eba\u6062\u5fa9\u6162\uff0c\u5289\u6021\u5747\u6559\u6388\u5be6\u9a57\u5ba4\u5728\u4e03\u5e74\u524d\u958b\u59cb\u9032\u884c\u9019\u9805\u7814\u7a76\uff0c\u767c\u73fe\u4e86\u4e00\u500b\u57fa\u56e0activating transcription factor 3\uff08ATF3\uff09\u53ef\u80fd\u8abf\u63a7\u5275\u50b7\u8a18\u61b6\u7684\u9069\u5ea6\u8868\u9054\u3002\u5728\u6b63\u5e38\u60c5\u6cc1\u4e0b\uff0cATF3\u53ef\u58d3\u6291\u6050\u61fc\u8a18\u61b6\u7684\u904e\u5ea6\u8868\u9054\uff0c\u4e00\u65e6ATF3\u57fa\u56e0\u7684\u529f\u80fd\u55aa\u5931\uff0c\u58d3\u6291\u4e0d\u4e86\u5275\u50b7\u8a18\u61b6\uff0c\u65bc\u662f\u9020\u6210\u4e86\u6050\u61fc\u8a18\u61b6\u904e\u5ea6\u8868\u9054\uff0c\u5275\u50b7\u5f8c\u58d3\u529b\u75c7\u5019\u7fa4\u7684\u75c7\u72c0\u96a8\u4e4b\u51fa\u73fe\u3002<\/p>\n<p>\u8a18\u61b6\u7684\u63d0\u53d6\u9700\u8981\u7d93\u904e\u6d77\u99ac\u8ff4\uff0c\u5289\u6021\u5747\u5be6\u9a57\u5ba4\u767c\u73feATF3\u9019\u500b\u57fa\u56e0\u4e0d\u4f46\u5728\u6d77\u99ac\u8ff4\u5167\u9ad8\u5ea6\u8868\u9054\uff0c\u4e26\u53ef\u8abf\u63a7\u8a31\u591a\u8207\u5275\u50b7\u5f8c\u58d3\u529b\u75c7\u5019\u7fa4\u76f8\u95dc\u7684\u57fa\u56e0\u8868\u9054\u3002\u900f\u904e\u8207\u53f0\u5317\u91ab\u5b78\u5927\u5b78\u6797\u6052\u6559\u6388\u7684\u5408\u4f5c\uff0c\u5289\u6021\u5747\u5be6\u9a57\u5ba4\u53d6\u5f97\u4e86\u5931\u53bbATF3\u57fa\u56e0\u7684\u5c0f\u9f20\u9032\u884c\u7814\u7a76\uff0c\u767c\u73fe\u9019\u96bb\u5c0f\u9f20\u679c\u7136\u8868\u9054\u8f03\u9ad8\u7684\u6050\u61fc\u8a18\u61b6\u3002\u5289\u6021\u5747\u5be6\u9a57\u5ba4\u9032\u800c\u7814\u7a76\u5176\u8abf\u63a7\u7684\u6a5f\u8f49\uff0c\u4e26\u4ee5\u85e5\u7269\u6291\u5236\u904e\u5ea6\u8868\u73fe\u7684\u6050\u61fc\u8a18\u61b6\uff0c\u4f7f\u5176\u56de\u5fa9\u6b63\u5e38\u3002\u5982\u679c\u80fd\u8abf\u7bc0\u6050\u61fc\u8a18\u61b6\u7684\u8def\u5f91\uff0c\u672a\u4f86\u53ef\u61c9\u7528\u65bc\u5275\u50b7\u5f8c\u58d3\u529b\u75c7\u5019\u7fa4\u53ca\u7126\u616e\u75c5\u60a3\u7684\u6cbb\u7642\u3002\u5289\u6021\u5747\u5f37\u8abf\uff0c\u9019\u9805\u7814\u7a76\u7d50\u679c\u4ecd\u9700\u9032\u4e00\u6b65\u7814\u7a76\u624d\u80fd\u5c07\u6b64\u985e\u85e5\u7269\u61c9\u7528\u65bc\u81e8\u5e8a\u3002<\/p>\n<p>\u9019\u9805\u7814\u7a76\u6b77\u7d93\u4e03\u5e74\uff0c\u5f9e\u7814\u7a76\u52a9\u7406\u958b\u59cb\u5230\u7814\u7a76\u751f\u63a5\u624b\uff0c\u8fd1\u5e7e\u5e74\u66f4\u52a0\u5165\u4e86\u5370\u5ea6\uff0c\u6cf0\u570b\u5b78\u751f\uff0c\u7d42\u65bc\u5728\u4eca\u5e74\u7372\u5f97\u570b\u969b\u5b78\u8853\u7684\u80af\u5b9a\u3002\u5289\u6021\u5747\u6559\u6388\u7684\u7814\u7a76\u5718\u968a\u5305\u62ec\u6148\u6fdf\u5927\u5b78\u5206\u5b50\u751f\u7269\u66a8\u4eba\u985e\u907a\u50b3\u5b78\u6240\u7684\u78a9\u58eb\u767d\u5609\u8056\uff0c\u5f90\u8207\u7db8\uff0c\u52a9\u7406\u9ec3\u7e96\u5a77\uff0c\u53ca\u6148\u5927\u5370\u5ea6\u7c4d\u7814\u7a76\u751fPranao Sharma\uff0cSrivashinavi Loganathan\uff0c\u8207\u6cf0\u570b\u7c4d\u535a\u58eb\u751fSarayut Phasuk\uff0c\u6148\u6fdf\u5927\u5b78\u9019\u5e7e\u5e74\u62db\u6536\u570b\u969b\u7814\u7a76\u751f\u7684\u7814\u7a76\u6210\u679c\u9010\u6f38\u5c55\u73fe\u3002<\/p>\n<p>\u7814\u7a76\u8ad6\u6587\u9023\u7d50\uff1a<a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnmol.2018.00037\/full?&amp;utm_source=Email_to_authors_&amp;utm_medium=Email&amp;utm_content=T1_11.5e1_author&amp;utm_campaign=Email_publication&amp;field&amp;journalName=Frontiers_in_Molecular_Neuroscience&amp;id=304113\" target=\"_blank\" rel=\"noopener\">https:\/\/www.frontiersin.org\/<\/a><\/p>\n<p><a href=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/024.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-2433 size-full\" src=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/024.jpg\" alt=\"\" width=\"1024\" height=\"683\" srcset=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/024.jpg 1024w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/024-300x200.jpg 300w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/024-768x512.jpg 768w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/024-730x487.jpg 730w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/024-435x290.jpg 435w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/024-272x182.jpg 272w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a> <a href=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/028.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-2434 size-full\" src=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/028.jpg\" alt=\"\" width=\"1024\" height=\"683\" srcset=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/028.jpg 1024w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/028-300x200.jpg 300w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/028-768x512.jpg 768w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/028-730x487.jpg 730w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/028-435x290.jpg 435w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/028-272x182.jpg 272w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a> <a href=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/LINE_P2018226_142606.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-2435 size-full\" src=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/LINE_P2018226_142606.jpg\" alt=\"\" width=\"1024\" height=\"683\" srcset=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/LINE_P2018226_142606.jpg 1024w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/LINE_P2018226_142606-300x200.jpg 300w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/LINE_P2018226_142606-768x512.jpg 768w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/LINE_P2018226_142606-730x487.jpg 730w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/LINE_P2018226_142606-435x290.jpg 435w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2018\/03\/LINE_P2018226_142606-272x182.jpg 272w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6587:\u674e\u5bb6\u8413 \u300c\u8001\u9f20\u770b\u5230\u8c93\u6703\u9003\uff0c\u807d\u5230\u5de8\u5927\u8072\u97ff\u6211\u5011\u6703\u7279\u5225\u8b66\u6212\uff0c\u9069 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2435,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-2432","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-5","clearfix"],"_links":{"self":[{"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/2432","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2432"}],"version-history":[{"count":1,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/2432\/revisions"}],"predecessor-version":[{"id":11579,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/2432\/revisions\/11579"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/media\/2435"}],"wp:attachment":[{"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2432"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2432"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2432"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}