{"id":18727,"date":"2025-04-30T11:16:49","date_gmt":"2025-04-30T03:16:49","guid":{"rendered":"https:\/\/newsletter.tcu.edu.tw\/?p=18727"},"modified":"2025-04-30T11:16:49","modified_gmt":"2025-04-30T03:16:49","slug":"%e3%80%8c%e7%94%9f%e7%89%a9%e9%86%ab%e5%ad%b8%e6%9a%a8%e5%b7%a5%e7%a8%8b%e5%ad%b8%e7%b3%bb%e5%b0%88%e9%a1%8c%e6%bc%94%e8%ac%9b%e3%80%8d-applications-of-3d-cell-culture-in-precision-medicine-research","status":"publish","type":"post","link":"https:\/\/newsletter.tcu.edu.tw\/?p=18727","title":{"rendered":"\u300c\u751f\u7269\u91ab\u5b78\u66a8\u5de5\u7a0b\u5b78\u7cfb\u5c08\u984c\u6f14\u8b1b\u300d Applications of 3D Cell Culture in Precision Medicine Research"},"content":{"rendered":"<p class=\"p1\"><span class=\"s1\">\u6587<\/span><span class=\"s2\">\/<\/span><span class=\"s1\">\u7167\u7247\uff1a\u751f\u7269\u91ab\u5b78\u66a8\u5de5\u7a0b\u5b78\u7cfb<\/span><\/p>\n<p class=\"p2\"><span class=\"s1\">\u96a8\u8457\u751f\u7269\u91ab\u5b78\u7814\u7a76\u7684\u767c\u5c55\uff0c\u4e09\u7dad\u7d30\u80de\u57f9\u990a\uff08<\/span><span class=\"s2\">3D cell culture<\/span><span class=\"s1\">\uff09\u9010\u6f38\u6210\u70ba\u5be6\u9a57\u5ba4\u4e2d\u91cd\u8981\u7684\u7814\u7a76\u5de5\u5177\u4e4b\u4e00\u3002<\/span><span class=\"s3\">\u91ab\u5de5\u7cfb\u5728\u9ad8\u6559\u6df1\u8015\u8a08\u756b\u7684\u7d93\u8cbb\u652f\u6301\u4e0b\u7279\u5225\u9080\u8acb<\/span><span class=\"s1\">\u65b9\u5713\u7d30\u80de\u751f\u91ab\u516c\u53f8\u7684\u8cc7\u6df1\u7814\u7a76\u54e1\u9ec3\u5f65\u5f70\u535a\u58eb\uff0c\u4ecb\u7d39\u8a72\u516c\u53f8\u6700\u65b0\u7814\u767c\u7684<\/span><span class=\"s2\">3D<\/span><span class=\"s1\">\u57f9\u990a\u6280\u8853\u61c9\u7528\u3002<\/span><\/p>\n<p class=\"p2\"><span class=\"s1\">\u76f8\u8f03\u65bc\u50b3\u7d71\u7684\u4e8c\u7dad\u7d30\u80de\u57f9\u990a\uff08<\/span><span class=\"s2\">2D cell culture<\/span><span class=\"s1\">\uff09\uff0c<\/span><span class=\"s2\">3D<\/span><span class=\"s1\">\u57f9\u990a\u7cfb\u7d71\u80fd\u66f4\u8cbc\u8fd1\u9ad4\u5167\u74b0\u5883\uff0c\u4f7f\u7d30\u80de\u5728\u4e09\u7dad\u7a7a\u9593\u4e2d\u6210\u9577\u3001\u5206\u5316\u8207\u4ea4\u4e92\u4f5c\u7528\u3002<\/span><span class=\"s2\">2D<\/span><span class=\"s1\">\u57f9\u990a\u65b9\u5f0f\u96d6\u7136\u6280\u8853\u6210\u719f\uff0c\u4f46\u7531\u65bc\u7d30\u80de\u591a\u534a\u8cbc\u9644\u65bc\u5e73\u9762\u3001\u8868\u9762\uff0c\u5bb9\u6613\u5931\u53bb\u539f\u672c\u7684\u751f\u7406\u884c\u70ba\u8207\u5f62\u614b\u7279\u5fb5\u3002<\/span><span class=\"s2\">3D<\/span><span class=\"s1\">\u7cfb\u7d71\u5247\u80fd\u63d0\u4f9b\u66f4\u771f\u5be6\u7684\u7d30\u80de\u9593\u4ea4\u4e92\u4f5c\u7528\u8207\u7d30\u80de\u5916\u57fa\u8cea\u7d50\u69cb\uff0c\u7279\u5225\u9069\u7528\u65bc\u7814\u7a76\u816b\u7624\u5fae\u74b0\u5883\u3001\u5e79\u7d30\u80de\u5206\u5316\u4ee5\u53ca\u85e5\u7269\u53cd\u61c9\u3002\u91dd\u5c0d\u76ee\u524d<\/span><span class=\"s2\">3D<\/span><span class=\"s1\">\u57f9\u990a\u5e38\u898b\u7684\u6280\u8853\u74f6\u9838\uff0c\u7279\u5225\u662f\u7d30\u80de\u61f8\u6d6e\u4e0d\u5b9a\u5c0e\u81f4\u5373\u6642\u89c0\u6e2c\u56f0\u96e3\u7b49\u554f\u984c\uff0c\u9ec3\u535a\u58eb\u7684\u516c\u53f8\u7814\u7a76\u5718\u968a\u8a2d\u8a08\u51fa\u4e00\u7a2e\u7279\u6b8a\u5857\u5c64\u6750\u6599\uff0c\u80fd\u5920\u61c9\u7528\u65bc\u57f9\u990a\u76bf\u8868\u9762\u4ee5\u7a69\u5b9a\u7d30\u80de\u7d50\u69cb\u3002\u900f\u904e\u6b64\u7a2e\u5857\u5c64\uff0c\u7d30\u80de\u5728\u5f62\u6210\u7403\u72c0\u6216\u5718\u584a\u7d50\u69cb\u6642\u4e0d\u6613\u6f02\u6d6e\u6216\u6563\u958b\uff0c\u6709\u52a9\u65bc\u9032\u884c\u9ad8\u89e3\u6790\u5ea6\u89c0\u5bdf\u8207\u6642\u9593\u5e8f\u5217\u5f71\u50cf\u5206\u6790\uff0c\u63d0\u5347\u5be6\u9a57\u7684\u53ef\u91cd\u8907\u6027\u8207\u6e96\u78ba\u5ea6\u3002<\/span><\/p>\n<p class=\"p2\"><span class=\"s1\">\u6f14\u8b1b\u4e2d\u63d0\u53ca\u5faa\u74b0\u816b\u7624\u7d30\u80de\uff08<\/span><span class=\"s2\">circulating tumor cells, CTCs<\/span><span class=\"s1\">\uff09\u65bc\u764c\u75c7\u8f49\u79fb\u904e\u7a0b\u4e2d\u7684\u91cd\u8981\u6027\u3002\u5728\u816b\u7624\u9032\u5165\u665a\u671f\u968e\u6bb5\u6642\uff0c\u90e8\u5206\u764c\u7d30\u80de\u53ef\u80fd\u812b\u96e2\u539f\u767c\u816b\u7624\uff0c\u9032\u5165\u8840\u6db2\u5faa\u74b0\u5f8c\u8f49\u79fb\u81f3\u5176\u4ed6\u5668\u5b98\u3002\u7531\u65bc<\/span><span class=\"s2\">CTCs<\/span><span class=\"s1\">\u5728\u6578\u91cf\u8207\u578b\u614b\u4e0a\u8b8a\u5316\u5927\uff0c\u89c0\u5bdf\u4e0a\u5177\u9ad8\u5ea6\u6311\u6230\u6027\u3002\u7d50\u5408\u7a69\u5b9a\u7684<\/span><span class=\"s2\">3D<\/span><span class=\"s1\">\u57f9\u990a\u6280\u8853\uff0c\u6709\u52a9\u65bc\u6a21\u64ec\u816b\u7624\u8f49\u79fb\u7684\u904e\u7a0b\u53ca\u5075\u6e2c\u662f\u4f55\u7a2e\u764c\u75c7\uff0c\u9032\u4e00\u6b65\u63a2\u7d22<\/span><span class=\"s2\">CTCs<\/span><span class=\"s1\">\u7684\u884c\u70ba\u6a21\u5f0f\u8207\u6f5b\u5728\u81f4\u75c5\u6a5f\u5236\uff0c\u5c0d\u764c\u75c7\u8a3a\u65b7\u8207\u6cbb\u7642\u7b56\u7565\u7684\u512a\u5316\u5177\u6709\u95dc\u9375\u610f\u7fa9\u3002<\/span><\/p>\n<p class=\"p2\"><span class=\"s1\">\u7d9c\u5408\u800c\u8a00\uff0c<\/span><span class=\"s2\">3D cell culture<\/span><span class=\"s1\">\u6280\u8853\u4e0d\u50c5\u80fd\u63d0\u5347\u7d30\u80de\u5be6\u9a57\u7684\u6a21\u64ec\u5ea6\u8207\u771f\u5be6\u6027\uff0c\u4e5f\u70ba\u672a\u4f86\u751f\u91ab\u7814\u7a76\u63d0\u4f9b\u66f4\u5177\u6f5b\u529b\u7684\u767c\u5c55\u65b9\u5411\u3002\u900f\u904e\u65b0\u578b\u5857\u5c64\u8207\u57f9\u990a\u6750\u6599\u7684\u5c0e\u5165\uff0c\u53ef\u6539\u5584\u50b3\u7d71<\/span><span class=\"s2\">3D<\/span><span class=\"s1\">\u7cfb\u7d71\u5728\u7a69\u5b9a\u6027\u8207\u89c0\u6e2c\u4e0a\u7684\u9650\u5236\u3002<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-18728\" src=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d39\u300creat-time-liquid-biopsy\u300d\u7684\u61c9\u7528\u65b9\u5f0f.jpg\" alt=\"\" width=\"1024\" height=\"683\" srcset=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d39\u300creat-time-liquid-biopsy\u300d\u7684\u61c9\u7528\u65b9\u5f0f.jpg 1024w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d39\u300creat-time-liquid-biopsy\u300d\u7684\u61c9\u7528\u65b9\u5f0f-300x200.jpg 300w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d39\u300creat-time-liquid-biopsy\u300d\u7684\u61c9\u7528\u65b9\u5f0f-768x512.jpg 768w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d39\u300creat-time-liquid-biopsy\u300d\u7684\u61c9\u7528\u65b9\u5f0f-730x487.jpg 730w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d39\u300creat-time-liquid-biopsy\u300d\u7684\u61c9\u7528\u65b9\u5f0f-435x290.jpg 435w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d39\u300creat-time-liquid-biopsy\u300d\u7684\u61c9\u7528\u65b9\u5f0f-272x182.jpg 272w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-18729\" src=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d39\u5229\u75283D\u57f9\u990a\u6280\u8853\u6a21\u64ec\u816b\u7624\u8f49\u79fb\u7684\u904e\u7a0b\u53ca\u5075\u6e2c\u764c\u75c7.jpg\" alt=\"\" width=\"1024\" height=\"683\" srcset=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d39\u5229\u75283D\u57f9\u990a\u6280\u8853\u6a21\u64ec\u816b\u7624\u8f49\u79fb\u7684\u904e\u7a0b\u53ca\u5075\u6e2c\u764c\u75c7.jpg 1024w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d39\u5229\u75283D\u57f9\u990a\u6280\u8853\u6a21\u64ec\u816b\u7624\u8f49\u79fb\u7684\u904e\u7a0b\u53ca\u5075\u6e2c\u764c\u75c7-300x200.jpg 300w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d39\u5229\u75283D\u57f9\u990a\u6280\u8853\u6a21\u64ec\u816b\u7624\u8f49\u79fb\u7684\u904e\u7a0b\u53ca\u5075\u6e2c\u764c\u75c7-768x512.jpg 768w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d39\u5229\u75283D\u57f9\u990a\u6280\u8853\u6a21\u64ec\u816b\u7624\u8f49\u79fb\u7684\u904e\u7a0b\u53ca\u5075\u6e2c\u764c\u75c7-730x487.jpg 730w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d39\u5229\u75283D\u57f9\u990a\u6280\u8853\u6a21\u64ec\u816b\u7624\u8f49\u79fb\u7684\u904e\u7a0b\u53ca\u5075\u6e2c\u764c\u75c7-435x290.jpg 435w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d39\u5229\u75283D\u57f9\u990a\u6280\u8853\u6a21\u64ec\u816b\u7624\u8f49\u79fb\u7684\u904e\u7a0b\u53ca\u5075\u6e2c\u764c\u75c7-272x182.jpg 272w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-18730\" src=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u8207\u73fe\u5834\u5e2b\u9577\u4e92\u52d5.jpg\" alt=\"\" width=\"1024\" height=\"683\" srcset=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u8207\u73fe\u5834\u5e2b\u9577\u4e92\u52d5.jpg 1024w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u8207\u73fe\u5834\u5e2b\u9577\u4e92\u52d5-300x200.jpg 300w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u8207\u73fe\u5834\u5e2b\u9577\u4e92\u52d5-768x512.jpg 768w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u8207\u73fe\u5834\u5e2b\u9577\u4e92\u52d5-730x487.jpg 730w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u8207\u73fe\u5834\u5e2b\u9577\u4e92\u52d5-435x290.jpg 435w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9ec3\u5f65\u5f70\u535a\u58eb\u8207\u73fe\u5834\u5e2b\u9577\u4e92\u52d5-272x182.jpg 272w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-18731\" src=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9080\u8acb\u65b9\u5713\u7d30\u80de\u751f\u91ab\u516c\u53f8\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d393D\u7d30\u80de\u57f9\u990a\u6280\u8853\u7684\u61c9\u7528.jpg\" alt=\"\" width=\"1024\" height=\"683\" srcset=\"https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9080\u8acb\u65b9\u5713\u7d30\u80de\u751f\u91ab\u516c\u53f8\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d393D\u7d30\u80de\u57f9\u990a\u6280\u8853\u7684\u61c9\u7528.jpg 1024w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9080\u8acb\u65b9\u5713\u7d30\u80de\u751f\u91ab\u516c\u53f8\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d393D\u7d30\u80de\u57f9\u990a\u6280\u8853\u7684\u61c9\u7528-300x200.jpg 300w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9080\u8acb\u65b9\u5713\u7d30\u80de\u751f\u91ab\u516c\u53f8\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d393D\u7d30\u80de\u57f9\u990a\u6280\u8853\u7684\u61c9\u7528-768x512.jpg 768w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9080\u8acb\u65b9\u5713\u7d30\u80de\u751f\u91ab\u516c\u53f8\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d393D\u7d30\u80de\u57f9\u990a\u6280\u8853\u7684\u61c9\u7528-730x487.jpg 730w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9080\u8acb\u65b9\u5713\u7d30\u80de\u751f\u91ab\u516c\u53f8\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d393D\u7d30\u80de\u57f9\u990a\u6280\u8853\u7684\u61c9\u7528-435x290.jpg 435w, https:\/\/newsletter.tcu.edu.tw\/wp-content\/uploads\/2025\/04\/\u9080\u8acb\u65b9\u5713\u7d30\u80de\u751f\u91ab\u516c\u53f8\u9ec3\u5f65\u5f70\u535a\u58eb\u4ecb\u7d393D\u7d30\u80de\u57f9\u990a\u6280\u8853\u7684\u61c9\u7528-272x182.jpg 272w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6587\/\u7167\u7247\uff1a\u751f\u7269\u91ab\u5b78\u66a8\u5de5\u7a0b\u5b78\u7cfb \u96a8\u8457\u751f\u7269\u91ab\u5b78\u7814\u7a76\u7684\u767c\u5c55\uff0c\u4e09\u7dad\u7d30 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":18728,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-18727","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-5","clearfix"],"_links":{"self":[{"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/18727","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18727"}],"version-history":[{"count":1,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/18727\/revisions"}],"predecessor-version":[{"id":18732,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/18727\/revisions\/18732"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/media\/18728"}],"wp:attachment":[{"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18727"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18727"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsletter.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18727"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}